Jonathan Licht named president, chief scientific officer at Van Andel Institute <p>Jonathan D. Licht was named president and chief scientific officer of the Van Andel Institute. Licht will begin his new role in early 2026. This content is for Group 1 - Individual Seat, Individual Subscription - Annual ($555), Individual Subscription - Monthly ($55), Introductory Subscription - non-renewing ($60), and Sponsored account members only. Visit the […]</p> <p>The post <a href="https://cancerletter.com/in-brief/20251031_6a/"… The Cancer Letter October 31, 2025 Original source
UIC, UI Health, and Cook County Health expand partnership to strengthen healthcare safety net <p>The University of Illinois College of Medicine and Cook County Health have expanded their collaborative partnership that began in 2021.  This content is for Group 1 - Individual Seat, Individual Subscription - Annual ($555), Individual Subscription - Monthly ($55), Introductory Subscription - non-renewing ($60), and Sponsored account members only. Visit the site and log in/register […]</p> <p>The post <a href="https://cancerletter.com/in-brief/20251031_6b/"… The Cancer Letter October 31, 2025 Original source
Teen Survivor of T-Cell Acute Lymphoblastic Leukemia Aims High After Stem Cell Transplant <p>Nolan Young has aspirations of a career in both the Air Force and FBI, and even at age 15 it’s easy to imagine him achieving these goals. After all, when you’ve already endured the rigors of chemotherapy, radiation, emergency surgeries, and a stem cell transplant for T-cell acute lymphoblastic leukemia (T-ALL) — all before high ... <a class="read-more" href="https://blog.dana-farber.org/insight/2025/10/teen-survivor-of-t-cell-acute-lymphoblastic-leukemia-aims-high-after-stem-cell-transplant/" title="Teen… Dana-Farber Cancer Institute October 29, 2025 Original source
Helping Older Adults with Cancer <p>Tammy Hshieh, MD, MPH, is the lead geriatrician for geriatric oncology at Dana-Farber, working with the programs for Older Adults with Hematologic Malignancy, Older Adults with Breast Cancer, and Older Adults with Gastrointestinal Cancers. As a physician-scientist, her research focuses on promoting healthier aging and improving cognition and function as well as understanding and preventing ... <a class="read-more" href="https://blog.dana-farber.org/insight/2025/10/helping-older-adults-with-cancer/" title="Helping… Dana-Farber Cancer Institute October 29, 2025 Original source
Teacher Returns to Education After a Whipple Procedure <p>Marsha Olsen’s grandmother always used to say, “You have one body, take good care of it.”  And for most of her life, Olsen has spread that message as a middle school physical education and health teacher instilling healthy habits in her students.   “I wanted all my students to have a positive experience in physical education, ... <a class="read-more" href="https://blog.dana-farber.org/insight/2025/10/teacher-returns-to-education-after-a-whipple-procedure/" title="Teacher… Dana-Farber Cancer Institute October 28, 2025 Original source
Scientists discover COVID mRNA vaccines boost cancer survival Researchers found that COVID-19 mRNA vaccines significantly increased survival in lung and skin cancer patients undergoing immunotherapy. The vaccine appears to prime the immune system in a powerful, nonspecific way, enhancing cancer treatment outcomes. If confirmed, the discovery could lead to a universal cancer vaccine and transform oncology care. ScienceDaily Cancer October 28, 2025 Original source
Real-World Outcomes of Ipilimumab Plus Nivolumab for Metastatic Renal Cell Carcinoma: A National Population-Based Cohort Study Introduction <p>Immune checkpoint inhibitors are a standard first-line treatment for metastatic renal cell carcinoma (RCC), with combination ipilimumab and nivolumab (ipi–nivo) widely recommended. However, real-world data on its use in Australia remain limited.</p> Objective <p>To evaluate real-world outcomes of ipi–nivo for metastatic RCC in the Australian healthcare setting.</p> Methods <p>We conducted a retrospective cohort study using nationally linked Pharmaceutical Benefits… Targeted Oncology October 28, 2025 Original source
Scientists turn “junk DNA” into a powerful weapon against cancer King’s College London researchers discovered that parts of our DNA once thought to be “junk” can actually help destroy cancer cells. In some blood cancers, damaged genes trigger chaos in these DNA segments, leaving cancer cells vulnerable. When scientists used existing drugs to block the cells’ repair systems, the cells collapsed. This finding could open the door to new treatments… ScienceDaily Cancer October 27, 2025 Original source
Animal instincts: Exploring nature’s oncologist <p>Can we pick apart how evolution has suppressed cancer in some species? Alex Cagen is attempting exactly that by going beyond mouse models… way beyond.</p> <p>The post <a href="https://news.cancerresearchuk.org/2025/10/27/animal-instincts-exploring-natures-oncologist/">Animal instincts: Exploring nature’s oncologist</a> appeared first on <a href="https://news.cancerresearchuk.org">Cancer Research UK - Cancer News</a>.</p> Cancer Research UK October 27, 2025 Original source
Cardiotoxicity Profiles of Osimertinib Compared with Other EGFR Tyrosine Kinase Inhibitors: A Real-World Comparative Incidence Analysis Background <p>Osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is the standard first-line therapy for EGFR-mutant non-small cell lung cancer (NSCLC). Emerging evidence suggests that it may be associated with increased cardiotoxicity; however, current evidence is conflicting, and a small sample size and a lack of direct comparisons with other EGFR-TKIs limit existing studies.</p> Objective <p>We aim… Targeted Oncology October 27, 2025 Original source
Phase 1 Study of Luvometinib Use in Pediatric Patients with Neurofibromatosis Type 1-Related Unresectable Plexiform Neurofibromas Background <p>Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by plexiform neurofibromas (PNs), which are present in 20–60% of NF1 and may cause potentially life-threatening complications. Complete surgical resection of these PNs is generally not feasible, and regrowth after incomplete surgical resection has been observed. Luvometinib is a novel, oral, highly potent selective MEK1/2 inhibitor that has shown activity… Targeted Oncology October 26, 2025 Original source
Variation in access to cancer treatments is unacceptable – what can the National Cancer Plan for England do to help? <p>The UK Government have a critical opportunity to tackle variation in access to cancer treatment across the UK. To achieve this successfully, here's what they need to consider.</p> <p>The post <a href="https://news.cancerresearchuk.org/2025/10/23/variation-in-access-to-cancer-treatments-is-unacceptable-what-can-the-national-cancer-plan-for-england-do-to-help/">Variation in access to cancer treatments is unacceptable – what can the National Cancer Plan for England do to help?</a> appeared first on <a href="https://news.cancerresearchuk.org">Cancer Research UK - Cancer… Cancer Research UK October 23, 2025 Original source
They found cancer’s hidden power hubs and learned how to melt them away Texas A&M researchers found that in an aggressive kidney cancer, RNA builds “droplet hubs” that activate tumor genes. By creating a molecular switch to dissolve these hubs, they stopped cancer growth in lab and mouse tests. The work reveals how RNA can be hijacked to fuel disease, and how breaking its scaffolding could lead to new therapies for multiple pediatric… ScienceDaily Cancer October 23, 2025 Original source
A model citizen for early detection <p>Fresh from her Impact Award, Professor Ruth Etzioni talks mathematical models, overdiagnosis and why modellers must explain their working…</p> <p>The post <a href="https://news.cancerresearchuk.org/2025/10/23/a-model-citizen-for-early-detection/">A model citizen for early detection</a> appeared first on <a href="https://news.cancerresearchuk.org">Cancer Research UK - Cancer News</a>.</p> Cancer Research UK October 23, 2025 Original source
This everyday vitamin could be the closest thing we have to an “anti-aging pill” A study found that daily vitamin D supplements helped slow telomere shortening—the cellular process linked to aging and disease. Researchers believe its anti-inflammatory effects may protect DNA. While results are promising, the ideal dose remains unclear, and experts stress that lifestyle choices still matter most for longevity. ScienceDaily Cancer October 22, 2025 Original source
Doctors just found a way to slow one of the deadliest prostate cancers A powerful new drug combination—niraparib added to standard prostate cancer therapy—has been shown to significantly delay disease progression in men with specific DNA repair gene mutations. In the large AMPLITUDE trial, patients receiving the combo lived longer without symptoms worsening and saw nearly a 50% risk reduction in BRCA-mutated cases. While side effects like anemia were more common, the results… ScienceDaily Cancer October 22, 2025 Original source
This simple innovation could change blood pressure testing forever Scientists from the University of Exeter has developed a precise method to interpret ankle blood pressure readings—an innovation that could transform care for people unable to have their arm blood pressure measured. By analyzing data from over 33,000 participants, researchers created an algorithm and online calculator that improves accuracy and could prevent thousands of misdiagnoses worldwide. ScienceDaily Cancer October 21, 2025 Original source
A wearable temperature-sensing patch could detect breast cancer earlier <p>With our funding, PhD student Marah Alassaf is developing an “electronic skin” patch designed to make breast cancer testing more comfortable and accessible.</p> <p>The post <a href="https://news.cancerresearchuk.org/2025/10/21/a-wearable-temperature-sensing-patch-could-detect-breast-cancer-earlier/">A wearable temperature-sensing patch could detect breast cancer earlier</a> appeared first on <a href="https://news.cancerresearchuk.org">Cancer Research UK - Cancer News</a>.</p> Cancer Research UK October 21, 2025 Original source
Brain fog during menopause? Here’s what’s really going on Menopause brings profound shifts not just in hormones but in the very structure of the brain. Scientists have found that gray matter in regions tied to memory and thinking can shrink, while white matter may show damage linked to blood flow issues. Yet there’s hope — evidence points to partial recovery and adaptive changes postmenopause. ScienceDaily Cancer October 21, 2025 Original source
Dana-Farber Research Uncovers Potential Targeted Therapy for Endometrial Cancer <p>Jessica St. Laurent, MD, was sure something had gone wrong. The results of an experiment she’d run showed that the cancer cells she was studying had abnormally high levels of a specific collection of proteins of interest to her team.  “I remember seeing the gradient and thinking, This can’t be right,” says St. Laurent, who ... <a class="read-more" href="https://blog.dana-farber.org/insight/2025/10/dana-farber-research-uncovers-potential-targeted-therapy-for-endometrial-cancer/" title="Dana-Farber… Dana-Farber Cancer Institute October 21, 2025 Original source