The impact of concomitant medications on treatment outcomes in patients with cancer receiving immune checkpoint inhibitors

<p>Nature Reviews Cancer, Published online: 03 December 2025; <a href="https://www.nature.com/articles/s41568-025-00890-z">doi:10.1038/s41568-025-00890-z</a></p>Concomitant medications are emerging as a modifiable prognostic factor for immune checkpoint inhibitor treatment outcomes. This Review by Stone et al. highlights the potential immunomodulatory interactions of commonly prescribed medications and supplements, and proposes strategies to make better use of this information to guide clinical care.