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Exploiting metabolic cell death for cancer therapy

Nature Reviews Cancer | November 7, 2025 | Boyi Gan

<p>Nature Reviews Cancer, Published online: 15 October 2025; <a href="https://www.nature.com/articles/s41568-025-00879-8">doi:10.1038/s41568-025-00879-8</a></p>In this Review, Mao et al. discuss the regulation and interplay of the metabolic cell death pathways ferroptosis, disulfidptosis and cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.

Topics: research

Read the full article at Nature Reviews Cancer