Background <p>Liver metastases of colorectal cancer are one of the leading causes of mortality in patients with colorectal cancer. Oncolytic virus immunotherapy has demonstrated significant potential in tumor treatment; however, most oncolytic viruses are currently administered via intratumoral injection, limiting their broader clinical application.</p> Methods <p>In this study, we used an oncolytic vaccinia virus VVLTK-STCN1L-mIL21 expressing interleukin-21 to treat a…
Vaccinia virus armed with IL-21 can cure murine colorectal cancer liver metastases via intravenous administration
Journal for ImmunoTherapy of Cancer | | Wang, N., He, Y., Yu, J., Xia, Y., Jia, Y., Liu, R., Zhang, Y., Liu, Y., Ning, S., Chard Dunmall, L. S., Zhang, Z., Wang, Y.
Topics: colorectal-cancer, liver-cancer, cervical-cancer, immunotherapy, new-technology, research
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