Thymic involution, characterized by adipose replacement of functional thymic tissue, is a broadly recognized feature of age-related immunosenescence. Currently, no established, non-invasive method measures residual thymus in adults, its relationship with host immunity, or its influence on tumor immunosurveillance, cancer outcomes, and treatment-related toxicities. In a multi-institutional cohort of patients with locally advanced non-small cell lung cancer (NSCLC), we created…
Thymus Composition, Disease Control, and Toxicity in Locally Advanced Lung Cancer
medRxiv Oncology | | Chaunzwa, T. L., Book, A. J., Garomsa, B., Meng, Y. J., Yang, E., Krishnan, G., Chidi, A., Kim, R., Ma, J., Riely, G. J., Huang, J., Simone, C. B., Shaverdian, N., Gomez, D. R.
Topics: lung-cancer, blood-cancer, prevention