BackgroundThe life expectancy of patients with diffuse IDH-mutant low-grade gliomas (IDHmt LGG) WHO grade 2 ranges from 5 to over 20 years. Tumor behavior, including spontaneous growth rate, varies even within homogeneously classified subtypes of oligodendroglioma and astrocytoma. Risk-adjusted treatment strategies are needed to avoid therapy-related toxicities, without compromising outcome. The spontaneous tumor volume growth rate (TVGR) serves as a…
Distinct molecular profiles characterize the spontaneous growth rate of IDHmt low-grade astrocytoma and oligodendroglioma, WHO grade 2
medRxiv Oncology | | Darlix, A., Bady, P., Deverdun, J., Le Bars, E., Coget, A., Meriadec, J., Carriere, M., Duffau, H., Hegi, M. E.
Topics: skin-cancer, brain-cancer, research