Background <p>Uveal melanoma is a rare melanoma subtype characterized by a liver-dominant pattern of metastasis which is associated with a lack of durable responses to immunotherapies. Adoptive cell transfer of autologous tumor-infiltrating lymphocytes (TILs) has been shown to induce responses in a subset of patients with metastatic uveal melanoma. The safety and feasibility of locoregional administration of TIL therapy via…
Phase I trial of locoregional administration of autologous tumor-infiltrating lymphocytes in patients with uveal melanoma and liver metastases (the HAITILS trial)
Journal for ImmunoTherapy of Cancer | | Nelson, A., Riise, R., Alsen, S., Wong, A., Carlson, P., Edman, S., Holgersson, J., Olofsson Bagge, R., Johansson, I., Sadik, M., Edenbrandt, L., Nilsson, L. M., Nilsson, J. A., Ny, L.
Topics: skin-cancer, liver-cancer, immunotherapy, clinical-trials, research
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