BackgroundPharmacogenomics has emerged as a crucial tool in precision medicine, offering the potential to personalise cancer treatments by predicting and managing therapy-induced toxicities. This systematic review examined the genetic basis of toxicities associated with radiotherapy, chemotherapy, and immunotherapy in solid tumours. MethodsA comprehensive literature search was conducted across PubMed, Google Scholar, and PharmKB databases, covering the period from December 2019…
From Genes to Personalized Cancer Care: A Systematic Review of Toxicity-Associated Genetic Variants in Solid Tumor Treatments
medRxiv Oncology | | Gonzalez-Hernandez, A., Escamilla-Sanchez, A., Perez-Ruiz, E., Rios, A., Frecha, C. A., Vaca-Paniagua, F., Barragan, I., Perdomo, S., Rueda-Dominguez, A., oliver, j.
Topics: cervical-cancer, immunotherapy, targeted-therapy, chemotherapy, radiation, new-technology, research