BackgroundTargeted therapies have transformed breast cancer management by focusing on molecular drivers such as HER2 amplification, hormone receptor signaling, and CDK4/6 pathways. They aim to increase disease control while reducing systemic toxicity compared to conventional chemotherapy. ObjectiveThis review assessed the effectiveness and safety of targeted therapies in advanced and metastatic breast cancer, with progression-free survival (PFS) as the primary outcome…
Impact of Targeted Therapy on Progression-Free Survival in Breast Cancer: A Decade of Evidence from Randomized and Clinical Trials
medRxiv Oncology | | Adesina, O. G., Nwagwuogbe, F.
Topics: breast-cancer, skin-cancer, cervical-cancer, targeted-therapy, chemotherapy, clinical-trials, research