Role of solute carrier family 7 member 7 in cancer: opportunities for tumor microenvironment research

<p>Cancer poses serious health risks to humans. The solute carrier (SLC) family is crucial for cancer development regulation. As a member of this family, SLC7A7 forms a heterodimer with SLC3A2 to transport cationic and neutral amino acids (AA) across the membrane, thereby maintaining cellular AA homeostasis. A recent study resolved the crystal structure of SLC7A7 and identified the key residues…