Comprehensive Atlas of Cancer-Type-Specific Molecular Features from Comparative Analysis of TCGA Data

Cancer-type-specific molecular alterations often reflect the unique biological context of their tissue of origin and are more likely to represent relevant drivers rather than passenger events. We analyzed data from The Cancer Genome Atlas (TCGA) spanning 39 cancer types and 6 molecular platforms to create a comprehensive atlas of cancer-type-specific molecular features through unified comparative analyses. Simple nucleotide variation analysis…