Clinical application prospects of Nectin-4 in pan-cancer: an analysis based on the Trialtrove database

Journal for ImmunoTherapy of Cancer | |

<p>This research analyzes the global landscape of clinical trials focusing on therapies targeting the Nectin cell adhesion molecule 4 (Nectin-4) across various malignancies, using data from the Trialtrove database. Analysis of 136 interventional trials reveals a rapidly expanding field dominated by antibody-drug conjugates, particularly in urothelial carcinoma, with significant activity in combination regimens and diverse therapeutic modalities under exploration. These…

Topics: skin-cancer, bladder-cancer, cervical-cancer, targeted-therapy, clinical-trials, new-technology, research