Background <p>The gut microbiota plays a critical role in regulating immune homeostasis and modulating responses to cancer immunotherapies. However, the impact of antibiotic-induced dysbiosis in patients with multiple myeloma (MM) treated with bispecific antibodies (BsAbs) remains unexplored. This multicenter, international study investigated whether antibiotic exposure prior to BsAb initiation alters the gut microbiome and affects clinical outcomes in patients with…
Antibiotic-associated dysbiosis and bispecific antibody outcomes in multiple myeloma
Journal for ImmunoTherapy of Cancer | | Corona, M., Garcia-Vicente, R., Saez-Marin, A. J., Ancos-Pintado, R., Rodriguez-Garcia, A., Arroyo, A., Blanco, A., Chari, A., Martin, T., Wolf, J., Rey-Bua, B., Mateos, M.-V., Kortüm, K. M., Riedhammer, C., Tamariz-Amador, L. E., Valencia, E., Rodriguez-Otero, P., San Miguel, J., Ibarra, G., Oriol, A., Cedena, M. T., Lopez-Munoz, N., Alonso, R., Calbacho, M., Sanchez-Pina, J. M., Linares, M., Martinez-Lopez, J.
Topics: blood-cancer, new-technology, research
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