Background <p>Immune-related hepatitis (ir-hepatitis) ranks among the most frequent adverse events of immune checkpoint inhibitors (ICIs). Limited knowledge exists regarding the incidence, characteristics, and treatment of patients having an inadequate response to initial therapy with steroids. Characterizing ir-hepatitis phenotypes and treatment responses can provide valuable insights for guiding treatment decisions and prognosis.</p> Methods <p>This is a prospective study including patients…
Prospective study of patients with immune checkpoint inhibitor-induced hepatitis; characterization of liver injury, outcome of therapy, and management of steroid-unresponsive and steroid-dependent hepatitis
Journal for ImmunoTherapy of Cancer | | Holmstroem, R. B., Teisner, A. S., Sweep, M. W. D., Noringriis, I. M., Khan, S., Aagaard, N. K., Karlström, J., Jurlander, R. S., Sohlin, J. E., Monberg, T. J., Vestergaard, C., Stoltenborg Granhoj, J., Stenbog, P., Toxvaerd, A., Hansen, A. B., Bjerring, P. N., Lorentzen, T., Thielsen, P., Bol, K., Jonsson, G., Ellebaek, E., Svane, I. M.
Topics: immunotherapy, research
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