[News] Donated sperm with TP53 mutation used to conceive at least 197 children

The Lancet Oncology | |

Sperm from an otherwise healthy sperm donor—some of which harboured the TP53 gene mutation that causes a 90% lifetime cancer risk due to development of Li Fraumeni syndrome if passed to conceived children—has been used to father at least 197 children across Europe. Some of these children have already died from various cancers, and others have developed one or more…

Topics: research