Primary and secondary pseudo-stability and progression after atezolizumab with and without bevacizumab

Journal for ImmunoTherapy of Cancer | |

Background <p>Atypical tumor response patterns associated with immunotherapies pose significant challenges for assessing treatment response and clinical decision-making. We characterized the epidemiology, clinical impact, and molecular determinants of pseudo-stability/progression after atezolizumab with and without bevacizumab across several histologies.</p> Methods <p>Post hoc individual-level analysis of 2980 patients across eight randomized trials of atezolizumab in non-small cell lung cancer, urothelial carcinoma, renal…

Topics: lung-cancer, skin-cancer, blood-cancer, bladder-cancer, cervical-cancer, immunotherapy, clinical-trials