<p>Patients with metastatic breast cancer (MBC) have limited opportunities for a cure, as they develop resistance to therapies and continually form new metastases. Clinical overt metastases emerge from metastasis-initiating cancer cells (MICs) that disseminate during breast cancer (BC) progression. Currently, there are no available therapies that inhibit MIC dissemination to prevent overt metastasis. We provide preclinical evidence that intratumoral (IT)…
Intratumoral dendritic cell immunotherapy controls dissemination of metastasis-initiating cancer cells, even in patients with metastatic breast cancer
Journal for ImmunoTherapy of Cancer | | Soyano, A., Lee, M. C., Han, H. S., Aldrich, A., Soliman, H., Olson-Mcpeek, S. K., Balsay-Patel, C. N., Aiello, P., Farrell, C. M., Weinfurtner, R., Burgos, E., Czerniecki, B. J., Ramamoorthi, G.
Topics: breast-cancer, blood-cancer, immunotherapy, research
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