Local and locoregional prostate cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up†

Annals of Oncology | |

Diagnosis of prostate cancer is primarily based on PSA testing, digital rectal examination (DRE) and imaging to select men for prostate biopsy. Moderately elevated PSA concentrations (3-10 ng/ml) have limited specificity for detection, indicating the need for more accurate biomarkers. PSA-density (PSA-D), derived from PSA level divided by prostate volume, can add value in predicting clinically significant disease.1 Several blood…

Topics: prostate-cancer, blood-cancer, targeted-therapy, research